A review on vaccine pharmacovigilance during covid-19

Pharmacovigilance is important for collecting, detecting, monitoring adverse events which the main objective. The reported should be assessed in order to know casual relationship and avoid unnecessary effects on recipient. Many people are vaccinating a short period, so it becoming much burden pharmacovigilance centers. international society of (ISOP), French national agency medicines health products safety (ANSM), many others were continuous collaboration taking initiatives identify efficacy vaccines provide answers raised questions respectively. Through pharmacovigilance, signals detected, identified. BioNTech/Pfizer-m-RNA, Moderna-mRNA vaccine, Covishield, Johnson Johnson, Vaxzevria, Sputnik V, Convidecia addressed. With BioNTech/Pfizer-m-RNA 12,249 ADRs, with vaccine 577 Covishield 447 653 Vaxzevria 743 ADRs reported. These resulted immune thrombocytopenic purpura, cerebrovascular events, thrombosis, thrombocytopenia, facial paralysis, deaths, other reactions may fatal. But less compared patients. All these maintained by Uppsala center.